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Koffee runs more than 100 times faster than current alternatives. It only takes minutes to run a simulation.
Our ground-breaking solution for unbinding kinetics enables pharma and biotech companies to iterate smarter, save time & money and derisk the drug discovery process
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Simulate unbinding kinetics within minutes. You can get valuable insights at several steps in the drug discovery process.
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Our solution can complement time consuming and expensive laboratory experiments, supporting faster design cycles and giving you key insights for more compounds.
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By gaining insights to a key measure such as unbinding kinetics earlier in the process, we enable you to de-risk drug discovery!
Our revolutionary unbinding kinetics solution comes with several benefits compared to current methods
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Koffee runs more than 100 times faster than current alternatives. It only takes minutes to run a simulation.
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We have performed thorough benchmarking to demonstrate performance. Comparison to experimental unbinding rates achieved excellent agreement across a range of systems.
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Koffee performs strongly across different target classes and diverse ligand chemistry. We have benchmarked across popular drug targets including kinases, GPCRs and molecular chaperones.
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Koffee is based on Kvantify’s novel dynamics engine that is intrinsically ready for quantum. Classical methods provide speed; quantum methods will bring accuracy.
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Koffee predicts unbinding kinetics rates, a key metric indicating how long a drug interacts with the target
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Koffee ranks ligands according to their kinetic profile, providing rational insights into which molecules to take forward in the drug discovery process
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Koffee inherently scales: large numbers of calculations can be run simultaneously to provide fast results even early in the drug design process
Our groundbreaking unbinding kinetics solution comes with several benefits compared to current methods